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Cannabinoid CBG has antibiotic properties

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Cannabinoid CBG has antibiotic properties

Researchers from McMaster University in Canada have found that cannabigerol (CBG) can defeat MRSA, an infection notorious for many traditional antibiotics.

MRSA Methicillin-resistant Staphylococcus aureus stands for methicillin-resistant Staphylococcus aureus. It is popularly known as the 'hospital bacteria' because it mainly causes outbreaks in hospitals. The MRSA bacteria is insensitive (resistant) to a treatment with antibiotics that resemble the drug methicillin, a group of drugs that is widely used. MRSA bacteria are part of the particularly resistant micro-organisms (BRMO).

CBD can defeat the MRSA bacteria family

Researchers at McMaster University in Canada say cannabigerol (CBG), a cannabinoid found in hemp and cannabis plants, has antibacterial properties and has been shown to beat a family of bacteria known as methicillin-resistant Staphylococcus aureus (MRSA).

The findings, published in the journal American Chemical Society Infectious Diseases, suggest that CBG could become a breakthrough treatment for MRSA, a notorious drug-resistant infection.

“In this study, we examined 18 commercially available cannabinoids and they all showed antibiotic activity, some much more than others. The one we focused on was a non-psychoactive cannabinoid called CBG, because it had the most promising activity. We synthesized that cannabinoid in large quantities, which gave us enough compound to go deep into the study. – Eric Brown, lead author and professor of biochemistry and biomedical sciences at McMaster

In the study, researchers managed to cure MRSA infections in mice using CBG, which "turned out to be great at fighting pathogenic bacteria," Brown said. "The findings suggest a real therapeutic potential for cannabinoids as antibiotics."

The research team noted that CBG's toxicity on host cells is a hiccup in their findings, but its antibiotic properties are more than enough to warrant further research.

"It opens a therapeutic window to develop this into a drug," said Brown. "The next steps are to try to make the compound better because it is more specific to the bacteria and has a lower risk of toxicity."

Researchers at McMaster University have been studying the antibiotic properties of cannabinoids for two years since Canada legalized cannabis nationwide.

Sources including GanjaPreneur (EN), HealthLine (EN), Interesting Engineering (EN), Kannabiz (img), The Guardian (EN)

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