How can CBD be helpful in treating low back pain?

by druginc

How can CBD be helpful in treating low back pain?

Cannabis has been used medicinally for thousands of years to treat numerous ailments and ailments. Even today, the plant is increasingly recognized for its diverse potential in a wide range of indications and problems, including low back pain. One of the most common reasons for using medicinal cannabis in countries within a legal framework is pain relief.

Research shows that the complaints of low back pain in primary care range between 6,8% and 28,4% in high-income countries, making it a significant health problem. While the causes of low back pain can vary, it is commonly associated with both physical and psychological stressors, making it difficult to identify effective treatment options.

Current Treatment Options for Low Back Pain

Due to the complex nature of conditions such as low back pain, interdisciplinary action is often required. This may include the use of drugs, including opioids and non-steroidal anti-inflammatory drugs (NSAIDs), in combination with behavioral therapies/talking. However, the long-term efficacy of these treatment options is often unreliable, making research into alternative treatment options an important area of ​​research.

Medical cannabis and low back pain

While whole plant medicinal cannabis has promising potential for treating some pain conditions, the product's psychoactive properties mean it is often considered a last resort, or completely ignored in many countries.

On the other hand, cannabidiol (CBD) – the second most abundant cannabinoid produced by the cannabis plant – are an interesting product thanks to its ability to communicate with our bodies through numerous routes and the degree of safety in taking it. The World Health Organization recommends that CBD is safe and well tolerated by both adults and children.

A recent scientific rationale was aimed at understanding how these interactions could make CBD an interesting product for the treatment of low back pain.

The findings of this study CBD for low back pain treatment

To understand the potential of cannabidiol for low back pain, researchers reviewed current evidence of CBD's analgesic, anti-inflammatory, and anxiety-reducing properties.

Endocannabinoid receptors (CB1 and CB2) that have been found to work may play a role in important pain mediation processes and neuroinflammatory modulation. CBD may also affect certain central dopaminergic neuronal pain circuits and be involved in the activation of the serotonin and vanilloid receptor (TRPV1) – a complex mechanism likely responsible for diminishing pain control and, perhaps, the placebo effect (through anxiety reduction).

In addition, previous studies seem to show beneficial interactions between endocannabinoids and inflammatory joint disease. The authors of this investigation suggest that these interactions CBD “a potential three-in-one solution for treating chronic pain and improving quality of life” could make.

Anecdotal evidence also suggests that “CBD may reduce acute anxiety, impair the consolidation of anxiety-inducing memories, and facilitate the expulsion of previously acquired anxiety-related impressions.” These properties make the compound a promising compound for the treatment of anxiety, fear and pain-related conditions.

In conclusion

Overall, current research shows that patients report beneficial effects on chronic pain using CBD treatments, which the researchers suggest are likely due to the improvement in insomnia, anxiety, cognition and/or mood. While preliminary evidence from in vitro and animal studies suggests that CBD could be an important area of ​​research for the treatment of low back pain in the future, further clinical evidence is needed to gain a clearer picture of the potential of this very interesting compound.

The researchers recommend that future interventional studies assessing the potential of CBD compared to opioids and NSAIDs should consider assessing multiple modalities of low back pain compared to just one outcome.

Sources including Canex (EN), NCBI (EN), TandfOnline (EN)

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