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Magic mushrooms safe for human consumption

by Ties Inc.

2019-12-30-Magic mushrooms safe for human consumption

A large-scale study shows that psilocybin, the psychoactive substance in magic mushrooms, is safe for consumption. This brings science one step closer to developing psychoactive substances to treat depression.

Volunteers who received doses of the psychedelic substance as part of a trial at Kings College in London (KCL) did not experience any serious side effects. Psilocybin is tipped as a potential pioneering agent for the treatment of mental disorders. It could replace drugs such as antidepressants. Some studies even suggest that it might help people with an addiction.

Research results

The results are promising because it could offer perspective for psychiatric patients who have not been helped by conventional therapy or drugs. The side effects of psilocybin treatment were limited to changes in sensory perception and mood. Not surprising for a psychedelic. However, the drug had no negative effects on the cognitive and emotional functioning of the 'guinea pigs'. This is in contrast to antidepressants, where people often experience a 'dull' feeling.

Dosage and treatment resistant depression

There were a total of 25 dosing sessions. In each session, six participants received a dose of 10 or 0 milligrams of psilocybin or a placebo. This was done during one-on-one session with a therapist of approximately six hours with a follo-up period of twelve weeks. The company behind the study is Compass Pahtways, which is closely followed in the US and has even been given special breakthrough therapy status by the Food and Drug Administration.

It is currently conducting phase two of the study across Europe and North America with 216 patients suffering from depression and not responding to existing treatments. "This study is part of our overall clinical development program for treatment-resistant depression," said Compass Pathways co-founder Dr. Ekaterina Malievskaia

Read more independent.co.uk (Source, EN)

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