Cannabigerol, or CBG, is a non-psychoactive cannabinoid typically found most commonly in low-THC and CBD strains, including hemp. Like THC, CBG interacts with cannabinoid receptors in the brain. However, CBG acts as a buffer for the psychoactivity of THC by working to alleviate the paranoia sometimes caused by higher THC levelss.
CBG works to combat inflammation, pain and nausea and works to slow cancer cell proliferation. Research has shown that it also significantly reduces intraocular pressure in the eye caused by glaucoma. Strains with high CBG content are beneficial for the treatment of conditions such as inflammatory bowel disease, Crohn's disease and cancer.
Effects and benefits
Research has shown that CBG is effective in the treatment of a variety of symptoms and conditions. Examples of conditions where CBG is particularly effective in relieving symptoms include: glaucoma, cancer, Crohn's disease, and irritable bowel syndrome.
CBG for pain relief
Cannabis is popular for its pain-relieving properties. One study found that 97% of patients who used cannabis used it for chronic pain. And a study from the National Academy of Sciences stated conclusively that cannabis is an effective pain treatment. This pain relief is often attributed to THC. But studies on CBG and CBGA suggest both of these offer pain-relieving benefits. One study even found that CBG was more effective at controlling pain than THC or CBD.
CBG is anti-inflammatory
Another potential use for both CBG and CBGA is as an anti-inflammatory agent. Scientists believe these compounds can help people with inflammatory conditions, such as inflammatory bowel disease (IBD). One study looked specifically at the effect of CBG on IBD. Scientists caused colitis in mice and looked for inflammatory markers. The researchers found that giving the mice CBG eased their inflammation. They proposed human trials that tracked this early indicator of success.
CBG for the brain
CBG is perhaps best known for its potential as a neuroprotectant. This may be due to the anti-inflammatory effect of CBG, as inflammation of the brain may play a role in neurodegeneration. Studies on the effect of CBG on mice mimicked Huntington's disease. Not only did CBG reduce inflammation, it was an active neuroprotectant against brain degeneration. In other cases, CBG has even been shown to promote neurogenesis, the growth of new brain cells.
CBG against cancer
CBG also shows promise as a cancer fighter. CBG can help by blocking the receptors that cause cancer cells to grow. In a study in mice with colorectal cancer cells, CBG was able to inhibit the growth of the cancer cells, slowing the progression of the disease. In addition, some laboratory studies have shown that CBG inhibits prostate cancer cell growth, while others show inhibition of oral cancer cells. While much research remains to be done, these studies show exciting potential for cancer treatment with CBG.
CBG for eye health
CBG may also help treat glaucoma because of the way it reduces intraocular pressure. Our eyes contain many endocannabinoid receptors that can be activated by cannabinoids such as CBG. When activated, the result may be a shift in intraocular pressure. Research shows that CBG can be particularly helpful in lowering pressure and speeding up fluid drainage.
Research also suggests that CBG may be an effective antibacterial agent, especially against strains of bacteria such as MRSA, which are resistant to common antibiotics. In fact, CBG's ability to fight against a certain class of bacteria, mycobacteria and fungi is superior to that of THC, CBD or CBC. Perhaps these properties can be used in the future to create a new antibacterial treatment.
Help with bladder problems
CBG can also be useful in bladder disorders. There are numerous anecdotal stories about cannabis helping patients with bladder problems. One study looked at the effects of four different cannabinoids (CBG, THCV, CBD and CBDV) on bladder contractions. The researchers found that CBG was most effective in inhibiting muscle contractions in the human bladder. They concluded that it may be helpful to treat this uncomfortable symptom of many bladder conditions.
CBG for psoriasis
Another condition that CBG may be able to help with is psoriasis. In this state, the normal mechanisms regulating skin development fail, leading to thickening and / or redness of the skin. But CBG inhibits this effect, which researchers say could prevent these symptoms. While more human studies are needed, CBG can be a useful tool in the fight against psoriasis.
CBG for anxiety and depression
Finally, researchers have noted that CBG can be helpful for emotional regulation. Studies in rats show that CBG inhibits the uptake of the neurotransmitters serotonin and GABA, which can lead to increased serotonin and GABA levels in the brain. This suggests that CBG may have antidepressant properties. And when it comes to GABA, CBG inhibits absorption more effectively than CBD or THC. This is promising news, as CBG is also not psychoactive, it could be a useful cannabinoid alternative to THC when it comes to relieving depression.
Use CBG yourself
While the studies above are somewhat limited and more research needs to be done to say conclusively that CBG can help with all of these problems, CBG holds great promise as a potential treatment for a wide variety of conditions and symptoms. If you suffer from any of the above conditions, CBG may be an option worth trying. Order the product online now drsmartshop.com or go to the shop in Rotterdam.