Idan ya zo ga cannabis, mafi yawan hankali ya mayar da hankali ga sassa biyu na shuka: tetrahydrocannabinol (THC), bangaren da ke haifar da "high" jin dadi, da cannabidiol (CBD), ɓangaren da aka saba amfani dashi don dalilai na magani. Ta yaya cannabidiol zai iya yaƙar ƙwayoyin cuta?
Kamar yadda kuka riga kuka sani, CBD yana jin daɗin shahara sosai a fagen lafiya. Ana amfani da shi a matsayin madadin magani ga yanayin da ya kama daga tashin zuciya zuwa ciwo mai tsanani. Wasu mutane ma suna samun taimako don kawar da alamun tunani kamar damuwa.
Har zuwa 2018, yana da wahala a sami amincewar gwamnati don nazarin CBD, don haka yawancinsa bincike amfani da shi sabo ne. Wani filin binciken da ya fito shine neman abubuwan da ke hana ƙwayoyin cuta.
CBD yana kashe kwayoyin cuta
Ya zama cewa CBD a zahiri yana yin kyakkyawan aiki mai kyau na kashe ƙwayoyin cuta - har ma da ƙwayoyin cuta waɗanda ke jure maganin rigakafi na gargajiya. Samun sabon makami akan waɗannan ƙwayoyin cuta zai iya ceton rayuka da yawa.
Wakilin zai iya kashe kwayoyin cutar Gram-positive da Gram-negative. Duk nau'ikan ƙwayoyin cuta biyu na iya zama juriya ga maganin rigakafi. Duk da haka, kwayoyin cutar Gram-tabbatacce yawanci suna tabbatar da wuyar kashewa saboda suna da kauri mai kauri.
Gram Positive vs Gram Negative Bacteria
Kalmar ta fito ne daga hanyar Gram, hanyar da ake amfani da ita don gano ƙwayoyin cuta a cikin nama. Rini yana manne da kwayoyin cutar Gram-tabbatacce kuma yana lalata su da violet mai haske. Kwayoyin gram-korau ba sa riƙe rini da kyau, don haka kawai za su bayyana a matsayin launin ruwan hoda.
A cewar wani bincike na 2021, ana buƙatar cannbidiol kaɗan don kashe yawancin ƙwayoyin cuta na Gram. Har ma yana iya lalata nau'ikan da suka zama masu juriya ga magunguna da yawa, kamar:
- Staphylococcus aureus (MRSA) mai jurewa methicillin, wanda ke haifar da cututtuka na staph
- Clostridioidez difficile, wanda ke haifar da cututtuka na hanji
- Streptococcus pneumoniae, wanda ke haifar da ciwon huhu ko pneumococcal meningitis, kamuwa da kwayar cutar da ke kewaye da kwakwalwarka da kashin baya.
Daga cikin kwayoyin cutar Gram-negative kuma an yi nazari, nau'ikan 20 sun tsira daga kamuwa da CBD. Wannan ba abin mamaki ba ne, tun da masana kimiyya ba su sami wani sabon maganin rigakafi don magance kwayoyin cutar Gram ba tun 1962.
M antimicrobial
Menene masu binciken suka sami mamaki? CBD na iya kashe nau'ikan ƙwayoyin cuta guda huɗu na Gram-korau, waɗanda dukkansu suna da tarihin juriya na ƙwayoyi kuma suna iya yin barazanar rayuwa:
- Neisseria gonorrhea, wanda ke haifar da gonorrhea ta hanyar jima'i
- Neisseria meningitides, wanda ke haifar da cutar sankarau ko kamuwa da cutar jini
- Moraxella catarrhalis, wanda ke haifar da mashako
- Leigionella pneumophila, wanda ke haifar da cutar Legionnaires
Gabaɗaya, cannabidiol yana nuna alƙawarin azaman wakili na antimicrobial. Masu binciken sun ba da rahoton rikice-rikice na sha'awa, wanda mafi mahimmancin su shine cewa kamfanin samar da magunguna Botanix ya ba da gudummawar yawancin binciken. Botanix yana yin dabarar da ke fuskantar gwaji na asibiti a halin yanzu.
Duk da haka, wasu nazarin ba tare da rikice-rikice na sha'awa ba sun ruwaito irin wannan binciken. Misali, wani binciken da aka yi a shekarar 2022 ya gano cewa CBD na iya yakar Salmonella typhimurium, kwayar cutar Gram-korau da ke afkawa ciki da hanjin ku. Kimanin kashi 59 cikin XNUMX na cututtukan salmonella masu jure wa ampicillin (wani kwayan cuta na musamman da ake amfani da su don magance salmonella) sune nau'in typhimurium.
Me yasa wannan ya shafi?
Cibiyar Kula da Cututtuka (CDC) ta kiyasta cewa mutane miliyan 2,8 suna kamuwa da kamuwa da ƙwayoyin cuta a kowace shekara, kuma kusan mutane 35.000 ke mutuwa daga waɗannan cututtukan. Cannabidiol da alama yana kashe yawancin nau'ikan ƙwayoyin cuta masu cutarwa, gami da:
- MRSA, wanda ke haifar da kimanin asibitoci 323.700 da mutuwar 10.600 a kowace shekara.
- Clostridioidez difficile, ya haifar da kimanin mutane 223.900 na asibiti da mutuwar 12.800 a kowace shekara.
- Streptococcus pneumoniae, wanda ke haifar da kimanin mutane 900.000 kuma yana kashe 3.600 a kowace shekara.
- Neisseria gonorrhea, wanda ke kamuwa da kusan mutane 550.000 a shekara.
Waɗannan lambobin sun fito ne daga rahoton CDC na 2019 Barazanar Juriya na rigakafi a cikin Amurka. MRSA musamman da alama yana da wahala sosai don haɓaka juriya ga CBD fiye da maganin rigakafi. Nazarin 2021 ya auna juriya na miyagun ƙwayoyi ta hanyar haɓaka MRSA a cikin jita-jita na petri da auna mafi ƙarancin maida hankali (MIC), ko adadin abubuwan da ake buƙata don kashe duk ƙwayoyin cuta a cikin tasa.
MIC na maganin rigakafi daptomycin ya karu sau 26 a cikin kwanaki 20 na bayyanar. Ma’ana, kwayoyin MRSA sun samu juriya sosai bayan kwanaki 20 wanda ya kai sau 26 na ainihin adadin daptomycin don kashe shi. A halin yanzu, MIC na cannabidiol kawai ya karu da kashi 1,5. Dangantakar magana, MRSA da kyar ta haɓaka juriya ga CBD.
Ta yaya CBD ke yaki da kwayoyin cuta?
Akwai wani abu na musamman game da yadda CBD ke aiki wanda ke sa ya fi wahala ga ƙwayoyin cuta su daidaita. Yawancin ƙwayoyin cuta masu juriya suna kare kansu ta hanyar hana maganin rigakafi shiga cikin ƙwayoyin su. CBD ba dole ba ne ya shiga cikin kwayoyin cutar don kashe shi. Maimakon haka, yana kai hari ga membranes na ƙwayoyin cuta kuma yana sa ƙwayoyin cuta su tashi kamar balloons na ruwa.
Wasu maganin kashe kwayoyin cuta na gargajiya, irin su penicillin, suma suna kashe kwayoyin cuta ta hanyar lalata mabobin jikinsu. Ƙarin bincike na iya taimaka wa masana su tantance takamaiman takamaiman ƙwayoyin CBD da kuma dalilin da yasa CBD ya bayyana ya fi tasiri fiye da maganin rigakafi wajen rushe wasu nau'ikan membranes na kwayan cuta.
CBD yana haɗuwa da sunadaran
Duk da wannan aikin lab mai ƙarfafawa, CBD ba ta shirye don amfani da ita a duniyar gaske azaman maganin rigakafin ƙwayoyin cuta ba. Wannan abu yana da babban rauni wanda ke hana shi zama maganin mu'ujiza: yana ɗaure sosai da sunadaran.
Lokacin da CBD ya shiga cikin jinin ku, zai haɗa da sunadaran a cikin plasma. CBD ba ya kashe sunadaran ɗan adam kamar yadda yake yin ƙwayoyin cuta, amma yana haɗawa da waɗannan ƙwayoyin. Kashi 10 zuwa 14 ne kawai ke zama 'marasa ruwa' kuma ana samun su don kai hari ga ƙwayoyin cuta.
A taƙaice, shan wiwi ko man CBD ba zai iya taimaka muku yaƙi da kamuwa da cuta ba. CBD yana yaduwa ta cikin jiki da yawa don kai hari ga ƙwayoyin cuta. Tabbas, bincike ya ci gaba. Masana kimiyya sun ci gaba da nazarin hanyoyin da za su yi amfani da damar CBD na yaki da kwayoyin cuta. Yiwuwar sun haɗa da hanyoyin jigilar CBD kai tsaye zuwa ƙwayoyin cuta idan akwai kamuwa da cuta, ko CBD na roba wanda ke watsi da sunadaran ɗan adam kuma kawai ke kai hari kan ƙwayoyin cuta.
Source: healthline.com (En)
