Johns Hopkins yana gwada marijuana na likita a matsayin magani mai mahimmanci don cutar ƙaiƙayi

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Johns Hopkins yana gwada marijuana na likita a matsayin magani mai mahimmanci don cutar ƙaiƙayi

Ciwan kai na yau da kullun - wanda aka sani a asibiti a matsayin mai saurin ciwan jiki - ana nuna shi azaman mara ƙarfi kuma wani lokacin har ma da jin daɗin rauni na ƙaiƙayi kuma sau da yawa yakan rage darajar rayuwa ga waɗanda ke fama da shi.

Kula da yanayin ya kasance da wahala saboda ƙarancin hanyoyin da aka ba da izinin Gudanar da Abinci da Magunguna. Yanzu, binciken binciken da aka yi kwanan nan daga masu bincike a Johns Hopkins Medicine ya ba da tabbaci cewa akwai yiwuwar akwai zaɓi mai fa'ida ga marasa lafiya masu fama da cutar: marijuana na likita (cannabis).

Shawn Kwatra, MD, mataimakin farfesa a fannin ilimin cututtukan fata a Johns Hopkins School of Medicine. "Tare da karuwar amfani da wiwi na likitanci da kuma fahimtar rawar da tsarin endocannabinoid ke ciki (wani hadadden siginar sigina da ke tsara ayyuka da yawa a cikin jiki) a cikin cutar ƙaiƙayi, mun yanke shawarar gwada tabar wiwi a cikin majiyyacin da ya kasa nasara kuma ba su da zaɓi kaɗan. ”

Binciken na baya-bayan nan ya binciki wata Ba-Amurke Ba'amurke 'yar shekara 10 wacce ke fama da cutar rashin lafiya tsawon shekaru XNUMX. Da farko majiyyacin ya isa Johnch Hopkins Itch Center tare da tsananin alamun alamun pruritus a hannunta, ƙafafunta da ciki. Binciken fata ya nuna raunuka masu yawa na fata. An yi amfani da magunguna daban-daban ga mai haƙuri - gami da wasu hanyoyin kwantar da hankali na yau da kullun, aikin feshin hanci, maganin mayukan steroid, da kuma maganin hoto - amma duk sun kasa.

Amfani da marijuana na magani nan da nan ya inganta ƙaiƙayin yau da kullun

Masu binciken sun ce amfani da tabar wiwi - ta hanyar shan sigari ko kuma a cikin ruwa - ya ba matar ci gaba nan take.

Daya daga cikin masu binciken ya ce: "Mun yi wa marassa lafiyar bayanin alamun ta ta amfani da ma'auni na lamba, inda 10 ya kasance mafi munin ciwo kuma sifili ba shi da ciwo ko kaɗan." “Ta fara ne a aji na 10, amma ta fadi zuwa kashi 10 na cutar cikin minti 4 bayan gudanarwar farko ta shan tabar wiwi. Tare da ci gaba da shan wiwi, ciwon mara lafiyar ya ɓace gaba ɗaya. ”

Masu binciken sun yi imanin cewa daya daga cikin abubuwan da ke aiki a cikin marijuana na magani, tetrahydrocannabinol - wanda aka fi sani da raguwar THC - yana jingina ga masu karɓar kwakwalwa wanda ke shafar tsarin jin tsoro. Lokacin da wannan ya faru, kumburi da tsarin tsarin juyayi suna raguwa, wanda kuma zai iya haifar da raguwa a cikin jin dadin fata kamar itching.

Kodayake har yanzu akwai tabbatattu bincike Ya kamata a yi don inganta marijuana na likita azaman ingantaccen ma'auni don sauƙin ƙaiƙayin da ba a iya shawo kansa ba, an yi imanin cewa ƙarin karatun asibiti tabbas yana da garanti.

"Ana buƙatar nazarin da za a sarrafa don sanin ƙayyadadden magani, inganci da amincin tabar ta likitanci a kula da ƙananan nau'ikan ƙaiƙayi na ɗan adam, kuma da zarar an gudanar da waɗannan za mu ƙara fahimtar waɗanda marasa lafiya za su iya cin gajiyar wannan maganin."

Har ila yau, a cikin Laburaren Magungunan Magungunan Magunguna na binciken bincike game da maganin cutar ƙaiƙayi

Ana samun wadatuwar tabar wiwi ta likita ga marasa lafiya a Amurka, kuma yanzu tunda an halatta marijuana na nishaɗi a cikin jihohi da yawa, sha'awar haƙuri na ƙaruwa. Tsarin endocannabinoid yana taka muhimmiyar rawa a cikin homeostasis na fata, ban da ƙarin fa'ida akan maganganun neurogenic kamar pruritus da nociception, kumburi da martani na rigakafi.

Har ila yau, a cikin Laburaren Magungunan Magungunan Magunguna na binciken bincike game da maganin cutar ƙaiƙayi
Har ila yau, a cikin Laburaren Magungunan Magungunan Magunguna na binciken bincike game da maganin cutar ƙaiƙayi (fig.)

Yawancin nazarin in vitro da dabbobin dabba sun ba da haske game da hanyoyin da za a iya canzawa na Cannabinoid a kan pruritus, tare da mafi yawan shaidu a bayan yanayin gyaran jijiyoyin ƙwayoyin cuta da ƙananan masu karɓar Cannabinoid.

Bugu da ƙari, nazarin a cikin mutane, yayin da iyakancewa saboda bambance-bambance a cikin cannabinoids da aka yi amfani da su, nau'in cututtuka da kuma hanyar gudanarwa, sun nuna ci gaba da raguwa a cikin kullun da kuma bayyanar cututtuka a cikin itching na kullum.

Nazarin asibiti ya nuna raguwar pruritus a cikin cututtukan fata daban-daban (atopic dermatitis, psoriasis, asteatotic eczema, prurigo nodularis da allergic contact dermatitis) da kuma tsari (uremic pruritus and cholestatic pruritus) cututtuka.

Waɗannan karatun ɗan adam na farko sun bada garantin karatu don tabbatar da fa'idar cannabinoids a cikin maganin pruritus kuma don daidaita tsarin kulawa da alamomi. A cikin marasa lafiya waɗanda ke da ƙarancin tsauraran matakai bayan ingantattun hanyoyin kwantar da hankali, ana iya yin la'akari da hanyoyin Cannabinoid a matsayin maganin tallafi yayin da doka ta tanada.

Ta haka ne rahoton bincike game da cutar yau da kullun a Babban dakin karatun likitanci.

Kafofin sun hada da AnalyticalCannabis (EN), Hopkins Magunguna (EN), KalmarKa (EN)

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