Bincike a cikin magunguna na tushen LSD ba tare da tasirin hallucinogenic ba

ƙofar Ƙungiyar Inc.

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Magunguna irin su namomin kaza na sihiri da LSD na iya yin aiki azaman masu ƙarfi da dorewa na antidepressants. Amma kuma suna haifar da illa masu canza tunani waɗanda ke iyakance amfani da su. Duk da haka akwai bege a sararin sama.

Masana kimiyya sun ba da rahoto a cikin mujallar Nature cewa sun ƙirƙiri magunguna bisa LSD waɗanda ke da alama suna kawar da damuwa da damuwa a cikin berayen ba tare da haifar da ruɗi na yau da kullun ba.

LSD amma daban-daban

"Mun gano cewa mahadi na mu suna da ainihin aikin antidepressant iri ɗaya kamar magungunan psychedelic," in ji Dr. Bryan Roth, marubucin binciken kuma farfesa a fannin harhada magunguna a Makarantar Magunguna ta UNC Chapel Hill. "Ba tare da illolin psychedelic ba."

Sakamakon binciken zai iya haifar da kwayoyi don damuwa da damuwa waɗanda ke aiki mafi kyau, da sauri, suna da ƙarancin illa kuma suna dadewa. Akwai bincike da yawa akan masu tabin hankali da illolinsu, amma bincike kan abubuwan da ba su da hallucination, samfuran irin wannan har yanzu ba su da yawa. A yunƙurin da ya gabata, an yi bambance-bambancen ibogaine ba tare da tasirin hallucinatory ba. An yi samfurin ne daga tushen haushin shukar ɗan ƙasa zuwa Afirka ta Tsakiya. Wanda aka fi sani da itacen iboga.

Sabon magani

Sabuwar maganin ta fito ne daga babban ƙungiyar masana kimiyya. Sun gina dakin karatu mai kama da na kwayoyin halitta miliyan 75 wadanda ke dauke da wani sabon tsari da aka samu a cikin wasu magunguna, gami da psychedelics psilocybin da LSD, maganin migraine (ergotamine) da magungunan ciwon daji, ciki har da vincristine.

Tawagar ta yanke shawarar mayar da hankali kan kwayoyin halittar da ke shafar tsarin serotonin na kwakwalwa, wanda ke da hannu wajen daidaita yanayin mutum. amma ba su neman maganin rage damuwa. Duk da haka, yayin da aikinsu ya ci gaba, ƙungiyar ta gane cewa wasu masu bincike sun nuna cewa psilocybin na maganin ƙwaƙwalwa na iya rage damuwa a cikin mutane. Bugu da ƙari, tasirin miyagun ƙwayoyi na iya ɗaukar lokaci mai tsawo.

Psilocybin a matsayin tushe

"Akwai rahotanni masu ban sha'awa na gaske na mutanen da ke samun sakamako mai kyau tare da wannan bayan kawai 'yan allurai," in ji Brian Shoichet, marubucin binciken kuma farfesa a sashen ilimin kimiyyar magunguna a Jami'ar California, San Francisco. Don haka ƙungiyar ta fara tace bincikensu don nemo ƙwayoyin cuta a cikin ɗakin karatu nasu waɗanda zasu iya aiki iri ɗaya.

An gano ƙwayoyin ƙwayoyin cuta guda biyu suna da matuƙar aiki don rage alamun damuwa a cikin beraye. Masana kimiya sun nuna cewa linzamin kwamfuta da ke danne yana saurin yin kasala da sauri idan aka sanya shi cikin wani yanayi mara kyau, kamar ratsa wutsiya. Amma wannan linzamin kwamfuta zai ci gaba da gwagwarmaya idan an ba shi maganin rashin jin daɗi kamar Prozac, ketamine ko psilocybin. Mice kuma sun ci gaba da gwagwarmaya lokacin da aka ba su kwayoyin gwaji.

Amma ba su nuna alamun sanin ilimin kwakwalwa ba, wanda yawanci yakan sa linzamin kwamfuta ya ja hancinsa ta hanya ta musamman. "Mun yi mamakin ganin haka," in ji Roth. Kungiyar ta ce tana bukatar tace wadannan sabbin kwayoyin halitta kafin a gwada su a jikin dan adam. Dalili ɗaya shine kamar suna kwaikwayi ikon LSD na ƙara yawan bugun zuciya da haɓaka hawan jini.

Shiriya da yawa

Bugu da ƙari ga waɗannan sakamako masu illa, maganin ƙwaƙwalwa a yanzu yana buƙatar kulawar likita da mai ilimin hanyoyin kwantar da hankali don jagorantar majiyyaci ta hanyar kwarewa ta hallicinatory. Idan ba tare da waɗannan tasirin ba, ana iya samun ƙarin ƙarin marasa lafiya.
Wani fa'idar sabuwar hanyar ita ce, tasirin antidepressant yana faruwa a cikin sa'o'i na shan miyagun ƙwayoyi kuma zai iya wuce shekara ɗaya ko fiye. Magunguna irin su Prozac da Zoloft sukan ɗauki makonni don aiki kuma dole ne a sha kowace rana.

Source: npr.org (En)

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