Mahalarta sun bayyana don haɓaka haƙuri ga LSD a tsawon lokacin binciken, tare da raguwar tasirin miyagun ƙwayoyi tare da kowane zama na gaba.
Microdosing yana da zafi. Sau da yawa bincike ne don yuwuwar fa'idodin shan ƙananan ƙwayoyin cuta akai-akai. Duk da haka, wani bincike na baya-bayan nan ya nuna cewa microdosing LSD zai iya haifar da wani irin juriya.
Haƙuri LSD
Wani sabon binciken ya gano cewa mutane na iya haɓaka juriya don ɗaukar ƙananan allurai na LSD akai-akai. Saboda haka, miyagun ƙwayoyi bazai haifar da gyare-gyare na dindindin ko canje-canje ba, masu bincike sun rubuta a cikin jarida Binciken Halitta.
"Sakamakon ya kasance mai ban takaici saboda ba mu ga wani gagarumin ci gaba a cikin yanayi ko fahimta ba, ko kuma da gaske canje-canje masu dorewa a cikin kowane matakan da muka duba," in ji jagoran bincike Harriet de Wit, farfesa a fannin ilimin hauka da halayyar kwakwalwa a Jami'ar Chicago..
A cikin binciken, an zaɓi mahalarta 56 bazuwar don karɓa akai-akai ko dai wani wuribo ko ƙananan ƙarancin LSD, 13 ko 26 micrograms. Idan aka kwatanta, mutane suna ɗaukar allurai na 100 zuwa 200 micrograms don haifar da balaguron hallucinogenic, in ji de Wit. LSD, gajeriyar lysergic acid diethylamide, an fara haɗa shi a cikin XNUMXs. Ba'amurke Cibiyar Intelligence ta tsakiya ya yi amfani da shi a cikin gwaje-gwajen sarrafa tunani a lokacin yakin cacar baka. A cikin sittin ya zama albarkatun hippie na gaske kuma yana nuna alamar al'ada.
Tasiri yana raguwa
An ba wa mahalarta binciken microdoses ɗin su a cikin lokuta huɗu daban-daban na sa'o'i biyar a cikin dakin gwaje-gwaje, kwana uku ko hudu tsakanin su. Ba a gaya musu irin nau'in maganin da ake gwadawa ba, don kada su bari tsammanin kansu ya yi tasiri ga sakamakon binciken, in ji de Wit.
Don tantance yanayin su da aikin tunanin su, mahalarta sun yi gwaje-gwajen kwakwalwa da ayyukan motsa jiki a lokacin zaman microdose da kuma lokacin zaman biyan kuɗi ba tare da kwayoyi ba. Binciken ya gano cewa microdosing LSD yana da lafiya, ba tare da wani mummunan tasiri akan yawan zuciya, hawan jini ko wasu alamun mahimmanci ba.
Amma mahalarta sun yi kama da haɓaka juriya ga LSD a tsawon lokacin binciken, tare da tasirin miyagun ƙwayoyi ya bayyana ya ƙare tare da kowane zama na gaba. "Mun ga wani tasiri lokacin da mutane suka fara samun shi," in ji de Wit. "Sun ji karin kuzari, sun ji karin kuzari da kuzari, amma wannan tasirin ya ragu kadan a cikin zaman guda hudu."
Amfani ko placebo?
Kodayake ana ɗaukar LSD a matsayin magani na Jadawalin 1 ta Hukumar Kula da Tilasta Magunguna ta Amurka (kayan da ba a yarda da amfani da magani ba da kuma babban yuwuwar cin zarafi), ana haɓaka microdosing azaman hanyar haɓaka ƙirƙira, sanya wani ya fi wayo ko kaifi, inganta yanayi. ƙwarewar zamantakewa, in ji masana.
A cewar Matthew Johnson, darektan Cibiyar Johns Hopkins don Binciken Hankali da Hankali a Baltimore da de Wit, akwai ingantaccen dalili na nazarin halittu don zargin cewa microdosing LSD na iya yin tasiri akan kwakwalwa.
"LSD yana aiki akan tsarin serotonin, kuma tsarin serotonin shima iri ɗaya ne na neurotransmitter inda antidepressants kamar SSRIs ke aiki, don haka akwai dalilin neurobiological don tunanin zai iya aiki."
Abin takaici, wannan sabon bincike yana ba da haske daban-daban akan microdosing mahadi. Ya bayyana aƙalla wani ɓangare na tasirin placebo. Johnson: "Tambayar da ta dace ita ce ko duka tasirin placebo ne. Ya zuwa yanzu, babu wani binciken da ya sami ainihin wata shaida don ɗaukar ko da ƙaramin sigina na fa'idodin microdosing. ”
Microdosing ko macrodosing
Ma'anar microdosing a zahiri ya saba wa binciken zamani game da magungunan hauka, inda ake gudanar da allurai masu yawa. Nazarin da aka yi amfani da manyan allurai na psilocybin da sauran mahaɗan mahaukata "sun nuna sakamako mai ban sha'awa ga jiyya," in ji Johnson.
Duk da wannan, masu bincike ba sa so su faɗi tabbatacciyar cewa microdosing ba ya aiki kwata-kwata, bisa sakamakon wannan binciken. Tsawon karatu zai iya ganin sakamakon microdosing akai-akai. Mutanen da ke fama da yanayin yanayi kamar damuwa ko damuwa na iya iya ganin ƙarin tasiri. Johnson: "Ba zai zama abin mamaki ba ko kadan cewa maganin da ke canza tsarin serotonin naka zai iya taimakawa tare da damuwa."
Kara karantawa akan upi.com (Source, EN)
