Ngokutsho kweDyunivesithi yaseSydney, i-cannabis isetyenziswe ngamayeza kangangamawaka eminyaka. Ityala lokuqala elibhaliweyo libuyela kwi-2800 BC xa uMlawuli uShen Nung, uyise weyeza laseTshayina, walifaka kwi-pharmacopoeia yakhe. Ngezantsi unokufunda ngakumbi malunga nesakhono sezonyango ezahlukeneyo ze-cannabinoids.
Iitekisi ezivela kwiinkcubeko emhlabeni jikelele-amaHindu amaIndiya, ama-Asiriya, amaGrike namaRoma-zibonisa ukusetyenziswa kwezonyango kwiimeko zempilo ezahlukeneyo, kuquka i-arthritis, ukudandatheka, ukuvuvukala, intlungu kunye ne-asthma.
Izinto ezinokubakho kwi-cannabis
Ukuza kuthi ga namhlanje sisaphanda kwaye sibhaqa iipropati zonyango lwe-cannabis† Into esiyaziyo ngokuqinisekileyo kukuba intsangu yenziwe ngamachiza amaninzi abizwa ngokuba zii-cannabinoids. Iikhompawundi kukholelwa ukuba zinoxanduva lweziphumo eziluncedo kwezonyango ze-cannabis. Nazi ezimbalwa zale khompawundi kunye nokusetyenziswa kwazo okunokwenzeka:
I-CBG ifumaneka kwixabiso elincinci kakhulu kwi-cannabis. Ngokuqhelekileyo malunga ne-1% yezithako ezisebenzayo, xa kuthelekiswa ne-15-25% ye-CBD okanye i-20-30% ye-THC. Nangona i-asethi enqabileyo, ifumana ukuqondwa ngenxa yeenzuzo zayo, kubandakanya ukukhululeka kweempawu kwizigulana ezinesifo sokukrala kwamathumbu, iglaucoma kunye nesifo sikaHuntington.
Kukholelwa ukuba i-CBC isebenza ngokubambisana nezinye ii-cannabinoids ukukhuthaza ukwenziwa ngcono kunye nokufunxwa kwezo zinto. Ibophelela kunye ne-receptors kwingqondo ehambelana nokuqonda intlungu, okwenza le cannabinoid ibaluleke kakhulu kwizifundo ezizayo.
I-CBN yenziwa xa i-THC iguga kwaye iqhekeka. Iintyatyambo ezindala ze-cannabis zinezixa eziphezulu ze-CBN ngenxa yesi sizathu. Abanye abasebenzisi bakhetha ukusebenzisa kunye / okanye iminyaka yobudala be-cannabis kwizixa ezikhulu ze-CBN ezenzayo. Ngelixa lisaphantsi kophando, uphononongo lwakwangoko lubonisa ukuba i-CBN inokuba ne-anticonvulsant, antibacterial, kunye ne-neuroprotective properties.
Ziziphi izibonelelo zonyango zeTHC?
Enye yezona cannabinoids ezaziwa kakhulu, i-tetrahydrocannabinol, ngumthombo wemiphumo ye-cannabis 'psychoactive. Enye yeenzuzo eziphambili ze-THC kukuphelisa iintlungu. Uphononongo lwe-2013 olwenziwa kwiYunivesithi yaseCalifornia, eDavis, iZiko lezoNyango lifumene ukuphucuka okukhulu kwiintlungu ze-neuropathic xa kusetyenziswa umthamo ophantsi we-cannabis vaporized.
I-THC ikwanciphisa isicaphucaphu kunye nokuhlanza, yonyusa umdla wokutya kwaye ingasetyenziswa njengoncedo olusebenzayo lokulala. Ngezi zizathu, i-THC ihlala isetyenziselwa ukuchasana neziphumo zamanye amayeza, njengalawo anikwe abaguli be-chemotherapy. Ikwayindlela eqhelekileyo yonyango kubantu abaneentlungu ezingapheliyo, ukuphazamiseka kwemizwelo, kunye nokuphazamiseka kokulala.
Ziziphi izibonelelo zonyango ze-CBD?
I-Cannabidiol mhlawumbi yeyona cannabinoid eyaziwayo yesibini. Yikhompawundi engeyiyo i-psychoactive ehlala ivunwa kwi-hemp kune-cannabis (ewe, zizityalo ezahlukeneyo!) Ngenxa ye-CBD ephezulu kunye nomxholo omncinci we-THC.
Ngokungafaniyo ne-THC, i-CBD ayisiyonto elawulwa ngurhulumente yeShedyuli 1, evumela abaphandi ukuba bafunde ngezibonelelo zonyango. Olunye lolona setyenziso luqhelekileyo lwe-CBD kukuxhalaba kunye nokudakumba. Isenokuba lukhetho oluthembisayo kubantu abanengxaki yoxinzelelo lwasemva kokwenzakala. Nangona ingelonyango, inokusebenza ukuthomalalisa ixhala kunye nokuphazamiseka kokulala okuhambelana ne-PTSD.
I-CBD ikwaluncedo ekupheliseni iintlungu, ngokuyinxenye kuba ithathwa njenge-anti-inflammatory, kwaye ezinye izifundo zibonise ukusebenza kwayo ekunyangeni iintlungu ze-neuropathic. Ngenxa yesi sizathu, isetyenziswe ngabaguli abane-arthritis.
I-CBD yamkelwe yi-FDA ukunyanga iintlobo ezimbini zesifo sokuwa phantsi kwegama le-brand Epidiolex. Kwizilingo zeklinikhi, yanciphisa ukuxhaphaka kokubanjwa kwizigulane ezine-Lennox-Gastaut syndrome okanye i-Dravet syndrome.
Ngaba i-CBD ingaKukhusela kwi-COVID?
Kwangoko kulo nyaka, abaphandi kwiDyunivesithi yaseChicago bafumanisa ukuba iidosi eziphezulu zokucoceka kwe-CBD zinokunceda ukuthintela usulelo lwe-COVID-19. I-CBD ibonise unxulumano olubi olululo kunye novavanyo oluqinisekileyo lwe-SARS-CoV-2 kwizigulana ezithatha iyeza lokuxhuzula elivunywe yi-FDA. Oku kukhokelele abaphandi ukuba bacebise ulingo lwezonyango lokuphanda ikhonkco phakathi kwe-CBD kunye ne-COVID-19.
Kwakhona, izazinzulu ezivela kwiYunivesithi yaseOregon State zapapasha uphando olwafumanisa ukuba i-hemp cannabinoids ithintele amandla entsholongwane okosulela abantu. Ngelixa ezi zizifundo zelebhu zombini - hayi ulingo lwezonyango - abaphandi bayaqhubeka nokuphonononga ikhonkco phakathi kwe-cannabinoids kunye ne-COVID-19.
Funda ngaphezulu lasvegassun.com (Umthombo, EN)
